Understanding the Connection Between Epilepsy and Mental Health
- Austin Cole
- Jul 9
- 3 min read
Updated: Aug 5
Why Epilepsy and Mental Health Often Go Hand-in-Hand

People with epilepsy experience anxiety and depression at twice the rate of the general population. Studies show:
27–35% of people with epilepsy experience depression.
20–25% have an anxiety disorder.
Why does this happen?
Unpredictable seizures create daily uncertainty and fear.
Loss of independence, such as the ability to drive or maintain steady employment.
Side effects of seizure medications can alter mood-regulating brain chemicals.
Emotional strain, medical side effects, and life limitations all contribute to higher mental health risks.
Recognizing the Signs of Anxiety and Depression

Knowing what to look for is the first step toward getting support.
Depression Symptoms:
Persistent sadness or emotional numbness.
Loss of interest in things you usually enjoy.
Low energy or fatigue.
Changes in sleep or appetite.
Difficulty focusing or making decisions.
Anxiety Symptoms:
Excessive worry or dread.
Restlessness or irritability.
Panic attacks.
Physical symptoms (e.g., tight chest, headaches, nausea, racing heart).
If these symptoms persist for more than two weeks and interfere with daily functioning, it could indicate a treatable mood disorder.
How Anxiety and Depression Affect Your Seizures
Mental health isn’t just about how you feel emotionally—it can influence your epilepsy management too.
Stress and poor sleep are major seizure triggers.
Skipping medication due to emotional distress increases seizure risk.
Research shows those with untreated depression tend to experience more frequent or severe seizures.
It can become a cycle: seizures trigger anxiety, and anxiety increases seizure likelihood.
Coping Strategies: Taking Care of Yourself

Managing your mental health is just as important as managing your seizures. Here’s how you can start building a foundation of emotional resilience:
Stress Management
Stress is a well-known seizure trigger and can intensify feelings of anxiety. Practicing stress reduction techniques can have a powerful impact. Try daily mindfulness practices like deep breathing or meditation to calm your nervous system. Even simple routines can help you feel more grounded and in control.
Building a Healthy Routine
A steady daily rhythm can support both emotional balance and seizure control. Aim for 7–9 hours of sleep each night, and try to go to bed and wake up at consistent times. Regular meals and moderate exercise help keep your energy levels stable. Avoid overloading on caffeine or staying up late with screens, as both can increase anxiety and lower seizure thresholds.
Staying Connected
Isolation can make depression and anxiety worse. Even though it may feel difficult, reaching out to someone you trust—whether it’s a friend, family member, or peer—can be incredibly helpful. Many people find relief in support groups, where shared experiences and understanding make it easier to open up. You don’t have to go through this alone.
Seeking Professional Help
If you’re feeling overwhelmed, working with a mental health professional can make a major difference. Therapies like Cognitive Behavioral Therapy (CBT) are proven to help reframe negative thoughts and build coping skills. Programs like Project UPLIFT are designed specifically for people with epilepsy. Medication may also be recommended and can be safely managed alongside your seizure treatment plan.
Practicing Self-Compassion
Living with epilepsy takes resilience—and sometimes, that means being gentle with yourself. Allow yourself room to have hard days without guilt. Celebrate small achievements, like going for a walk or finishing your morning routine. Reflecting on daily moments of gratitude can shift your mindset and build emotional strength over time.
❝ Mental health care is health care. You deserve both. ❞
Where to Find Immediate Help and Ongoing Support

If you’re in crisis or need someone to talk to, reach out:
Epilepsy Foundation 24/7 Helpline: 1-800-332-1000 (English), 1-866-748-8008 (Spanish)
Suicide & Crisis Lifeline: Dial 988 anytime.
Other Support Avenues:
Events hosted by organizations like Young Adults With Epilepsy
Conclusion
Anxiety and depression are not weaknesses; they are challenges that many young adults with epilepsy face. Just like your physical health, your emotional well-being deserves consistent care and attention. With the right tools, professional help, and social support, you can manage your mood and improve your overall quality of life. Even small actions can lead to big changes.
Epilepsy Foundation. Missed Medicines and Seizure Risk. Epilepsy Foundation. https://www.epilepsy.com/what-is-epilepsy/seizure-triggers/missed-medicines
Epilepsy Foundation. Project UPLIFT: Using Practice and Learning to Increase Favorable Thoughts. Epilepsy Foundation. https://www.epilepsy.com/stories/project-uplift-using-practice-and-learning-increase-favorable-thoughts
Hesdorffer, D. C., Hauser, W. A., Annegers, J. F., & Cascino, G. (2000). Major depression is a risk factor for seizures in older adults. Annals of Neurology https://doi.org/10.1002/1531-8249(200002)47:2<246::AID-ANA17>3.0.CO;2-E47:2<246::AID-ANA17>3.0.CO;2-E)
Qin, S.-K., Yang, Z.-X., Guan, Z.-W., Zhang, J.-H., Ping, X., Lu, Y., … et al. (2022). Exploring the association between epilepsy and depression: A systematic review and meta-analysis https://doi.org/10.1371/journal.pone.0278907
Sleep Education. (2023). A Lack of Sleep May Trigger Seizures in Epilepsy. Sleep Education. https://sleepeducation.org/a-lack-of-sleep-may-trigger-seizures-in-epilepsy/
Verywell Mind. An Overview of the Treatments for Depression. https://www.verywellmind.com/treatments-for-depression-1065502
Verywell Health. (2022). How to Identify Your Epileptic Seizure Triggers. https://www.verywellhealth.com/epilepsy-triggers-6834004